Clinical evidence supports Magnetic Compression Anastomosis as a safe, effective, and reproducible treatment option for complete bile duct transections and complex benign biliary strictures. With high procedural success rates and encouraging long-term outcomes, MCA has the potential to transform the future of minimally invasive biliary intervention and improve quality of life for patients worldwide.
Evidence Backed MCA Technology
Why patients trust us with their care
The Magnetic Compression Anastomosis (MCA) platform developed by Ansh Endo Magnets is supported by prospective clinical research evaluating its safety, efficacy, and long-term outcomes in patients with complete bile duct transections and high-grade benign biliary strictures.
Study Overview
A prospective, open-label, multi-centre clinical study was conducted between January 2024 and June 2025 to assess the effectiveness of MCA in patients who had failed conventional endoscopic treatment. The study included patients aged 18 to 65 years with complete benign biliary strictures and a planned follow-up period of 24 months.
Patient Population
- Total Patients Enrolled: 26
- Mean Age: 44.03 years
- Female Patients: 16
- Male Patients: 10
Underlying Conditions
- Post-Cholecystectomy Biliary Strictures: 18 patients
- Benign Biliary Strictures: 5 patients
- Post-Liver Transplant Biliary Strictures: 3 patients
Clinical Outcomes
- Successful Recanalization Rate: 83%
- 24 out of 26 patients achieved successful biliary recanalization.
- Mean Recanalization Time: 21.5 days
- Average time required for successful recanalization.
Stricture Characteristics
- Mean Stricture Length: 12.04 mm
- Most Common Strasberg Classification: E2
- Additional Types Treated: E1, E4, and E5
Long-Term Follow-Up Results
Patients were followed for up to 24 months to assess durability and long-term patency.
Follow-Up Outcomes
- 7 of 8 patients became stent-free
- No restenosis observed in stent-free patients
- Sustained biliary patency maintained
- Encouraging long-term clinical outcomes
Post-Procedure Management
Following successful MCA treatment:
- Fully Covered Self-Expandable Metal Stents (FCSEMS): 16 patients
- Multiple Plastic Stents: 13 patients
Safety Profile
The procedure demonstrated an excellent safety profile with no significant post-procedural symptoms in most patients.
Observed Minor Adverse Events
- Mild abdominal discomfort
- Low-grade fever
- Minimal PTBD tract bleeding
- No major device-related complications reported
Clinical Significance
The study demonstrated that Magnetic Compression Anastomosis (MCA) provides a minimally invasive and effective alternative to surgical reconstruction in patients with refractory benign biliary strictures. The technology successfully addressed severe strictures that are difficult to traverse using conventional guidewire-based techniques.
Key Clinical Benefits
- High recanalization success rate
- Minimally invasive treatment approach
- Reduced need for major surgery
- Excellent safety profile
- Shorter recovery period
- Improved patient comfort
- Durable long-term outcomes
- Potential for stent-free recovery